Open AccessIDENTIFICATION OF CELLS OBTAINED FROM BLOOD OF ONCOLOGICAL PATIENTS WITH HEMOCYTOFILTRATION
Author(s) -
О. Г. Григорук,
A. F Lazarev,
A. A. Chimitov,
Т. Д. Ханхашанова,
Л. М. Базулина,
Ya. N. Shoikhet
Publication year - 2018
Publication title -
rossijskij onkologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2412-9119
pISSN - 1028-9984
DOI - 10.18821/1028-9984-2018-23-2-84-89
Subject(s) - peripheral blood , circulating tumor cell , pathology , tumor cells , identification (biology) , immunocytochemistry , biology , medicine , cancer research , immunology , cancer , metastasis , botany
This article presents the outcomes of our own research of the detection of circulating cells in the peripheral blood of 48 patients with oncological diseases, using hemocytofiltration. The observed circulating cells (21 cases, 43.8%) have been represented by three variants: more often in the form of “bare” atypical nuclei (76.2% cases), also single conserved tumor cells (14.3%) and large shapeless single cells, probably of non-epithelial nature (9.5%). The difficulties of identifying the obtained cells in light microscopy and technical aspects of the usage of immunocytochemical techniques have been discussed.