Open AccessTHE EROSIVE ULCEROUS LESIONS OF UPPER PART OF GASTROINTESTINAL TRACT IN PATIENTS WITH ISCHEMIC HEART DISEASE: TREATMENT AND PREVENTION
Author(s) -
N.V. Lareva,
N.V. Lareva,
A.A. Zhilina,
Е. Б. Жигжитова,
Elena E. Ustinova
Publication year - 2017
Publication title -
rossijskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2412-9100
pISSN - 0869-2106
DOI - 10.18821/0869-2106-2017-23-6-327-330
Subject(s) - medicine , aspirin , gastroenterology , pantoprazole , gastrointestinal tract , misoprostol , disease , helicobacter pylori , peptic ulcer , ischemia , peptic , omeprazole , pregnancy , abortion , biology , genetics
The erosive ulcerous affections of gastrointestinal tract in patients with cardiovascular diseases occur frequently and are conditioned by both ischemia of organs of digestion against the background of reduced cardiac output and intake of low doses of acetylsalicylic acid combined with anti-coagulants. The bleeding can be the first and the only manifestation of gastroduodenal pathology. The treatment and prevention of aspirin-induced gastropathy provides for implementation of eradication of Helicobacter pylori infection, application of cyto-protectors (Misoprostol or Bismuthate tripotassium dicitrate), long-term using of inhibitors of proton pump. Out of them Pantoprazole has a certain advantage at the expense low risk of medicinal interactions, good clinical efficiency and anti-inflammatory effect.