Open AccessThe clinical aspects of effectiveness of incretin therapy (WNT-pathogenic path and polymorphism of gene TCF7L2)
Author(s) -
А.С. Аметов,
Л Л Камынина,
Z.G. Akhmedova Akhmedova
Publication year - 2016
Publication title -
rossijskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2412-9100
pISSN - 0869-2106
DOI - 10.18821/0869-2106-2016-22-1-47-51
Subject(s) - tcf7l2 , incretin , wnt signaling pathway , type 2 diabetes mellitus , diabetes mellitus , medicine , polymorphism (computer science) , type 2 diabetes , gene , bioinformatics , genetics , biology , endocrinology , genotype , single nucleotide polymorphism
The article considers genetic susceptibility to development of diabetes mellitus type II, its micro-vascular complications and intensity of response under application of incretin therapy depending on carriage of polymorphism of gene TCF7L2 involved into WNT-path and incretin axis.