Open AccessThe idle possibilities of laboratory diagnostic under treatment of patients with drug resistant tuberculosis
Author(s) -
С. А. Попов,
T.P. Sabgayda,
Г. Н. Можокина
Publication year - 2016
Publication title -
rossijskij medicinskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2412-9100
pISSN - 0869-2106
DOI - 10.18821/0869-2106-2016-22-1-42-47
Subject(s) - tuberculosis , causation , regimen , drug resistance , drug , drug resistant tuberculosis , medicine , intensive care medicine , pharmacology , mycobacterium tuberculosis , surgery , biology , political science , pathology , genetics , law
The article presents analysis of publications’ data related to problem of implementation of personified treatment of patients with tuberculosis. This kind of treatment is conditioned by fast development and propagation of drug resistance of M.tuberculosis and by complexity of selecting effective regimen of treatment of these patients. The technical possibilities are demonstrated suitable for implementation of such approach. The directions are determined concerning additional research in area of evaluation of impact effectiveness and pharmacokinetic parameters for large specter of anti-tuberculosis pharmaceuticals, agent drug resistance to them and genetic causation of development of negative side-reactions to chemotherapy.