Open AccessLUJO HEMORRHAGIC FEVER
Author(s) -
Т. Е. Сизикова,
В. Н. Лебедев,
S. I. Syromyatnikova,
S. V. Borisevich
Publication year - 2017
Publication title -
voprosy virusologii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.151
H-Index - 15
eISSN - 2411-2097
pISSN - 0507-4088
DOI - 10.18821/0507-4088-2017-62-4-149-153
Subject(s) - arenavirus , viral hemorrhagic fever , lassa fever , medicine , lassa virus , virology , diarrhea , myalgia , transmission (telecommunications) , virus , immunology , ebola virus , lymphocytic choriomeningitis , electrical engineering , antigen , cd8 , engineering
Lujo hemorrhagic fever (LHF) is a viral disease accompanied with fever, headache, vomiting, diarrhea, arthralgia, myalgia and numerous signs of hemorrhagic syndrome. LHF causes a clinical syndrome remarkably similar to Lassa hemorrhagic fever. The first case of LHF occurred in Johannesburg, South Africa, in 2008. There was a secondary transmission from the index patient to four healthcare workers. Four of the five patients died. The etiologic agent of LHF is Lujo virus (LUJV) belonging to Arenavirus genus of the Arenaviridae Family. Virus Lujo is the second pathogenic arenavirus, after Lassa virus, to be recognized in Africa during the last 40 years. Data about epidemiology, clinical characteristics and diagnostics of LHF, properties of Lujo virus (according to phylogenetic analysis), and recommended precautions for preventing secondary transmission are considered in this paper.