Open AccessTHE EXPLORATION OF ETIOLOGICAL STRUCTURE OF SEXUALLY TRANSMITTED DISEASES IN PATIENTS OF ONCOLOGIC INSTITUTE
Author(s) -
Г. А. Неродо,
Tatyana A. Zykova,
Maksim N. Duritskiy,
Vyacheslav A. Sustretov,
Vera P. Nikitina,
Anna P. Menshenina,
Olga A. Bogomolova,
Polina A. Kruze
Publication year - 2019
Publication title -
zdravoohranenie rossijskoj federacii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.164
H-Index - 3
eISSN - 2412-0723
pISSN - 0044-197X
DOI - 10.18821/0044-197x-2018-62-2-68-75
Subject(s) - genitourinary system , medicine , population , etiology , chlamydia trachomatis , immunology , sexually transmitted disease , physiology , human immunodeficiency virus (hiv) , syphilis , environmental health
The attention to the problem of studying etiologic structure and patterns of prevalence of sexually transmitted infections is conditioned by their high morbidity, affection of population of reproductive age mainly and aftermath effecting health of people and their posterity. The polymerase chain reaction in real-time was applied to detect DNA of agents of sexually transmitted diseases in patients with inflammatory and oncologic diseases of urogenital tract. It was established that 55.4% of patients (64.6% females and 35.0% males) were infected by agents from group of sexually transmitted diseases. The mixed infections made up to 53.0% (54.9% females and 45.5% males). The index of prevalence of C. trachomatis in total cohort of examined individuals is equal to 2.2%. The age and gender differences were established concerning rate of detection of DNA of agents of sexually transmitted diseases. The DNA of C. trachomatis and viruses of herpes simplex type I and II was registered more often in males and the DNA of U. parvum/urealyticum, G. vaginalis, M. hominis, Candida spp. and cytomegalovirus - in females. The decreasing of amount of total bacterial mass and lactobacteria was established in all female patients with oncologic diseases. In females of this group the index of total prevalence of urogenital infections is 1.4 times lower than in group with inflammatory pathologies. The rate of mixed infections has factually no differences (52.9% and 55.2% correspondingly) and the level of detection of DNA of virus of human papilloma against the background of sexually transmitted diseases on the contrary is 1.7 times higher. In females being in menopause period total prevalence of agents of sexually transmitted diseases and rate of mixed infections were lower than in female patients of reproductive age.