Open AccessThe mortality of diseases of blood circulatory system in cohort of workers of enterprise of nuclear industry
Author(s) -
Tamara V. Azizova,
E. S. Grigoryeva,
М. Б. Мосеева,
К. В. Кузнецова,
Е П Фомин
Publication year - 2019
Publication title -
zdravoohranenie rossijskoj federacii
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.164
H-Index - 3
eISSN - 2412-0723
pISSN - 0044-197X
DOI - 10.18821/0044-197x-2016-60-6-317-324
Subject(s) - circulatory system , medicine , cohort , radiological weapon , cohort study , surgery
The study was carried out to investigate dynamics of mortality of diseases of blood circulatory system and to evaluate effect of radiological and non-radiological factors on indices of mortality because of diseases of blood circulatory system. The mortality of diseases of blood circulatory system (1CD-10 codes 100-199) was analyzed on cohort of 22,377 workers of enterprise of nuclear industry "Mayak" exposed to professional prolonged radiation. The study used individual estimates of doses of external and internal radiation using new dosimetry system of workers of "Mayak"-2008. The statistical analysis included calculation of non-standardized and standardized indices of mortality per 100,000 working people. The standardization was implemented by indirect technique using internal standard. To the end of observation period in studied cohort of workers 5 010 deaths because of diseases of blood circulatory system were registered as main cause of death during 836,048 man-years of observation. The standardized indices of mortality of diseases of blood circulatory system in males were statistically significant higher as compared with females and increased with augmentation of attained age of workers. The mortality of diseases of blood circulatory system depended statistically significant on non-radiation risk factors (smoking, alcohol consumption, increased body mass index, arterial hypertension). The indicator of mortality of diseases of blood circulatory system was statistically significant higher in males exposed to prolonged external gamma-radiation in total dose higher than 0.5 sieverts as compared with workers exposed to radiation in doses of 0.2-0.5 sieverts. The mortality of diseases of blood circulatory system was statistically significant higher in workers exposed to internal alpha-radiation in total absorbed dose more than 0.025 sieverts as compared with workers exposed to radiation in lesser doses. In the cohort of workers exposed to professional prolonged radiation mortality of diseases of blood circulatory system depended on both non-radiation and radiation factors.