Open AccessComparison of efficiency of a new sucrosomal
peroral form of iron with intravenous ferrotherapy in the treatment of anemia in inflammatory bowel diseases.
Author(s) -
Н. И. Стуклов,
Oleg Knyazev,
А И Парфенов,
I. G. Basiladze,
А В Пивник
Publication year - 2018
Publication title -
kliničeskaâ medicina
Language(s) - English
Resource type - Journals
eISSN - 2412-1339
pISSN - 0023-2149
DOI - 10.18821/0023-2149-2017-95-12-1112-1117
Subject(s) - medicine , anemia , gastroenterology , hemoglobin , iron deficiency anemia , malabsorption , iron deficiency , inflammatory bowel disease , intravenous iron , serum iron , hepcidin , hematinic , disease
The article describes the role of iron deficiency in the development of anemia in inflammatory bowel diseases (IBD), existing approaches to treatment. The problems of insufficient effectiveness and poor tolerance of standard iron preparations are discussed, which is associated with the presence of malabsorption and chronic inflammation of the intestinal wall. The aim of the work was to determine the effectiveness of a standard approach to treatment with intravenous iron preparations in comparison with the new sucrsomal oral form of iron Sideral Forte in patients with anemia in IBD. The materials of the study included data from 57 patients with anemia and IBD. The results of examination of 28 patients and treatment of 29 patients with anemia and IBD were analyzed, of which 14 received Sideral Forte, 15 intravenous ferrotherapy. According to the results of the study, it is proved that in the IBD hypo-normochromic and micro-normocytic anemia is always associated with a violation of iron metabolism. The results of the application of these groups of iron preparations for 3 months showed a significant increase in the concentration of hemoglobin, serum iron, a more significant effect of the sucrsomal oral iron for normalization of the hemoglobin concentration.