
Primary cardiac amyloidosis.
Author(s) -
И. В. Демко,
L. I. Pelinovskaya,
И. А. Соловьева,
А. Yu. Kraposhina,
Н. В. Гордеева,
В. А. Мосина
Publication year - 2018
Publication title -
kliničeskaâ medicina
Language(s) - English
Resource type - Journals
eISSN - 2412-1339
pISSN - 0023-2149
DOI - 10.18821/0023-2149-2017-95-11-971-976
Subject(s) - amyloidosis , cardiac amyloidosis , amyloid (mycology) , medicine , pathology , gold standard (test) , al amyloidosis , biopsy , disease , immunology , immunoglobulin light chain , antibody
Cardiac amyloidosis - the disease which is characterized by deposition of insoluble protein amyloid in intercellular space is one of the most severe implications of systemic amyloidosis. Primary cardiac amyloidosis possesses a wide range of clinical implications that complicates well-timed diagnostics and, respectively, treatment. The long latent current and the adverse forecast do extremely important diagnostics of cardiac amyloidosis at early stages of a disease. The modern concept of pathogenesis and morphology of an amyloidosis is covered in article, the clinical options of a current, diagnostic methods of dysfunction of heart including bio- and immunochemical blood analysis and urine, a complex of tool methods of a research and «the gold standard» of verification of deposits of amyloid - a biopsy of various organs and tissues are described.