Open AccessCOMPLEX OF HAZARD CRITERIA FOR IMPROVEMENT OF HYGIENIC STANDARDS LIST OF CHEMICALS IN WATER
Author(s) -
Roman A. Mamonov,
З. И. Жолдакова,
О. О. Синицына,
S. M. Yudin,
Irina A. Pechnikova
Publication year - 2019
Publication title -
gigiena i sanitariâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.275
H-Index - 13
eISSN - 2412-0650
pISSN - 0016-9900
DOI - 10.18821/0016-9900-2017-96-11-1099-1102
Subject(s) - hazard , risk analysis (engineering) , index (typography) , environmental science , computer science , hazard analysis , biochemical engineering , toxicology , business , reliability engineering , biology , engineering , ecology , world wide web
Analysis of domestic (Russian) and foreign documents revealed the necessity to correct existing standards of chemicals in water according to the new data about previously unexplored toxicological properties including mutagenic, carcinogenic effects, effects on the endocrine system. It is advisable to correct safety levels within the structural sets based on the relationship “structure- biotransformation-activity”. It is necessary to review critically the MACs of aromatic compounds substantiated on the organoleptic sign of harmfulness. The standards of nine carcinogens are proposed to revise with considering the classification and safety levels. Determination of threshold concentration on general sanitary index of harmfulness may be excluded from the regulation system because self-purification processes not sufficient in the Russian climatic conditions are related to ecological indices. This hazard index creates a discrepancy between the assessment of the danger of drinking and surface waters. It is necessary to create unified MACs for groups of substances in view of the forms of their presence in water and matching of toxic mechanism of action in compliance with the principle “unity of standard and method of control”.