Open AccessChanging of physico-chemical parameters of non-contact (electrochemical) activated drinking water is associated with induction of genomic instability of cultivated human blood lymphocytes
Author(s) -
О. В. Зацепина,
Faina I. Ingel
Publication year - 2019
Publication title -
gigiena i sanitariâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.275
H-Index - 13
eISSN - 2412-0650
pISSN - 0016-9900
DOI - 10.18821/0016-9900-2016-95-3-233-241
Subject(s) - genome instability , cytochalasin b , micronucleus , bottled water , micronucleus test , instability , tap water , human blood , chemistry , microbiology and biotechnology , biology , biophysics , in vitro , dna , dna damage , biochemistry , physiology , environmental science , toxicity , environmental engineering , physics , organic chemistry , mechanics
In the article there are presented data which are the fragment of large multidisciplinary study of genetic safety of noncontact electrochemically activated water (NAW). The aim of this study was the analysis of the relation of impacts of genomic instability (micronucleus test with cytochalasin B) detected in human blood cells, cultured in medias prepared on the base of these NAWs, with physical and chemical properties of these NaWs. In experiments there were used catholytes and anolytes obtained by activation of osmotic, tap and dining bottled water. As a result of such activation, all waters were shown to acquire the ability to induce genomic instability in cellular cultures. Notably in cell cultures on catholytes and anolytes these effects differed between themselves and have been associated with different physical and chemical properties of the NAWs.