Open AccessAn assessment of the immune status of the children population as a marker of technogenic pollution of the environment
Author(s) -
Л. А. Степаненко,
М. Ф. Савченков,
Светлана Владимировна Ильина,
Е. В. Анганова,
Е. Д. Савилов
Publication year - 2019
Publication title -
gigiena i sanitariâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.275
H-Index - 13
eISSN - 2412-0650
pISSN - 0016-9900
DOI - 10.18821/0016-9900-2016-95-12-1129-1133
Subject(s) - immunology , immune system , pollution , population , air pollution , antigen , environmental health , biology , medicine , ecology
This article describes results of the immunological study of school-aged children residing in cities with different levels of the technogenic air pollution. Children from cities with the highest level of the technogenic pollution had a high number of immature neutrophils (band cells) and eosinophils. The children living in these ecologically unfavorable areas have presented a reduction of T-cell antigen receptor CD3, CD4, CD8, CD20, CD16, CD95. This indicates to that both T-cell and B-cell immunity is suppressed. The decline of the phagocytic function in neutrophils indicates to the suppression of the nonspecific host defense mechanisms also.