Open AccessOvarian Insulin-Like Growth Factor-I
Author(s) -
M. Bijna,
K. Karthiayini
Publication year - 2020
Publication title -
agricutural science digest/agricultural science digest
Language(s) - English
Resource type - Journals
eISSN - 0976-0547
pISSN - 0253-150X
DOI - 10.18805/ag.d-5104
Subject(s) - growth factor , paracrine signalling , insulin like growth factor , autocrine signalling , medicine , endocrinology , biology , microbiology and biotechnology , follicular phase , receptor
The insulin-like growth factor-I is a pleotropic growth factor that modulates cell replication. Insulin-like growth factor-I is produced by granulosa, theca and luteal cells and have autocrine and paracrine actions. It plays a crucial role in animal fertility acting as a monitoring signal. Researches have shown that synergistically with gonadotropins it stimulates the growth, survivability and steroidogenesis of follicular cells.