Open Access<sup>68</sup>GA-PSMA — LABELED BIOMARKER FOR POSITRON EMISSION TOMOGRAPHY (LITERATURE REVIEW)
Author(s) -
М. Д. Пойда,
Д. В. Рыжкова,
А. А. Станжевский
Publication year - 2018
Publication title -
translâcionnaâ medicina
Language(s) - English
Resource type - Journals
eISSN - 2410-5155
pISSN - 2311-4495
DOI - 10.18705/2311-4495-2018-5-5-46-52
Subject(s) - positron emission tomography , prostate cancer , nuclear medicine , medicine , biomarker , positron emission , positron emission tomography computed tomography , positron , cancer , radiology , chemistry , physics , nuclear physics , biochemistry , electron
The review is devoted to the analysis of the diagnostic efficiency of combined positron emission and computed tomography (PET / CT) with the radiopharmaceutical 68 Ga-PSMA in the initial staging of prostate cancer in middle- and high-risk patients, the determination of the tumor focus in the biochemical recurrence of the disease, and monitoring the effectiveness of systemic and radionuclide therapy. The causes of false positive and false negative results of PET / CT are listed and indications for the procedure are presented as well. 68 Ga-PSMA diagnostic possibilities as a labeled biomarker of neovascularization in malignant neoplasms of other localizations are briefly described.