Open AccessReduced renal function in hypertension in young adults: a systematic review
Author(s) -
A. D. Khudyakova,
Yu. I. Ragino
Publication year - 2022
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2021-27-6-617-627
Subject(s) - renal function , blood pressure , medicine , concomitant , inclusion and exclusion criteria , hypertensive nephropathy , kidney , nephropathy , intensive care medicine , endocrinology , pathology , diabetic nephropathy , alternative medicine , diabetes mellitus
Objective. The aim of the systematic review was to find an answer to the question: «does an increased blood pressure affect kidney function at young age?». Design and methods. The following key words were used to search for relevant publications: “hypertensive nephropathy”, “reduction of glomerular filtration rate in arterial hypertension” in Russian and English. We used “eLIBRARY.RU — SCIENTIFIC ELECTRONIC LIBRARY” and PubMed.gov databases. The inclusion criteria were the young age of the examined patients (from 18 to 44 years), the absence of concomitant pathology. The analysis included only publications of the last 5 years (2015-2020). Results. A total of 18 articles were selected from Russian and international databases that meet inclusion criteria. Conclusions. Based on the analysis of the literature of the last 5 years we assume that increase in blood pressure disrupts kidney function in young people. However, the current data a number of limitations. Until now, gender characteristics, risk factors for decreased renal function in hypertension in young people, and most importantly, the pathogenetic basis of renal dysfunction remain unclear.