Open AccessStatins in patients with acute ischemic stroke: when we should start therapy?
Author(s) -
С. Н. Янишевский,
Я. Б. Скиба,
А. Ю. Полушин
Publication year - 2021
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 5
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2021-27-1-16-28
Subject(s) - medicine , ischemic stroke , stroke (engine) , statin , secondary prevention , ischemia , cardiology , intensive care medicine , mechanical engineering , engineering
Lipid-lowering therapy is known to be an important part of ischemic stroke secondary prevention, however, the exact timing of its initiation or re-starting in the patients with ischemic stroke is not yet defined strictly. Accumulating evidence of pleiotropic (i. e. non-lipid-lowering) effects of statins in various conditions, including ischemia, urges their implementation in the clinical practice. In this review, we discuss the evidence on the effectiveness of early statin introduction in different populations of patients with ischemic stroke. We also attempt to define our original position on the optimal time after the acute onset of neurological symptoms to introduce lipid-lowering therapy.