Arterial hypertension in a patient with non‑ specific aortoarteritis (Takayasu disease) and AA-amyloidosis: a case report

Arterial hypertension (HTN) is the most common cardiovascular disorder around the world. High blood pressure is a manifestation of essential hypertension (EHTN) in the majority of cases. The exclusion of symptomatic HTN is crucial for correct diagnosis. We present a case of a very rare symptomatic HTN caused by nonspecific aortoarteritis (Takayasu disease). Morphological substrate of Takayasu disease is arteritis associated with the total wall damage of aortic brunches. The diagnosis is very difficult due to the chronic course, nonspecific signs and a variety of clinical masks. That often leads to late diagnosis and complications. Clinical features of Takayasu aortoarteritis include unilateral pulse weakening, blood pressure asymmetry on right and left arms, bruit on damaged artery, laboratory signs of inflammation: accelerated erythrocyte sedimentation rate (ESV), anemia, thrombocytosis, C‑reactive protein (CRP) elevation. Ultrasound vessel duplex scanning is important, but angiography of aorta and aortic branches are still the “gold standard”. We draw attention to clinical features, diagnostic methods and the course of the Takayasu disease in a young woman with high blood pressure.