Open AccessPLASMA RENIN ASSESSMENT AS THE STRATEGY OF HYPERTENSION MANAGEMENT
Author(s) -
Юлия Викторовна Котовская,
О. А. Кравцова,
E. Pavlova
Publication year - 2013
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 5
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2013-19-5-380-388
Subject(s) - plasma renin activity , renin–angiotensin system , medicine , aldosterone , blood pressure , endocrinology
The recent interest to plasma renin activity (PRA) is due to the opportunity of antihypertensive therapy choice that is based on the understanding of the interrelation between renin-angiotensin-aldosterone system (RAAS) and mechanisms of water balance mediated by the renal sodium absorption and water retention. PRA is the way to understand the primary mechanism of blood pressure elevation. PRA < 0,65 ng/ml/h indicates the water retention, and hypertension is considered low-renin and «volume-dependent». If PRA is more than 0,65 ng/ml/h hypertension results from excessive renin secretion and RAAS activation.