Open AccessMAGNETIC RESONANCE SPECTROSCOPY IN EVALUATION OF COGNITIVE FUNCTIONS IN PATIENTS WITH METABOLIC SYNDROME
Author(s) -
Ирина Борисовна Зуева,
Надежда Морошкина,
Е. Р. Баранцевич,
Г. Е. Труфанов
Publication year - 2013
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 5
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2013-19-1-51-58
Subject(s) - cognition , neuropsychology , magnetic resonance imaging , proton magnetic resonance , functional magnetic resonance spectroscopy of the brain , psychology , cognitive impairment , neuropsychological testing , nuclear magnetic resonance spectroscopy , medicine , cognitive decline , neuroscience , functional magnetic resonance imaging , dementia , nuclear magnetic resonance , radiology , disease , physics
Objective. To evaluate the role of magnetic resonance spectroscopy (MR-spectroscopy) in the study of cognitive functions in patients with metabolic syndrome (MS). Design and methods. The study included patients with MS (10 patients without cognitive impairment and 11 subjects with cognitive dysfunction). All patients underwent neuropsychological testing, and cognitive evoked potential for the assessment of cognitive functions. Brain metabolism was studied by proton MR-spectroscopy. Results. In patients with MS and cognitive impairment, and without cognitive dysfunction no morphological changes in the brain according to the magnetic resonance imaging (MRI) were found. According to MR-spectroscopy of the brain in patients with MS and cognitive dysfunction the metabolism impairment is primarily associated with the increase in lactate and inositol. Conclusion. Indicators of neuropsychological testing, the cognitive evoked potential are associated with the violation of brain metabolism in patients with MS and cognitive impairment.