Open AccessAssociation of cognitive function with cardiovascular risk factors in middle age individuals
Author(s) -
Ирина Борисовна Зуева,
К. И. Ванаева,
E. L. Sanez,
V. Piotrovskaya,
Eugene Genikhovich,
Victoria Kirillova,
E. Shlyakhto
Publication year - 2011
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 5
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2011-17-5-432-440
Subject(s) - blood pressure , cognition , medicine , association (psychology) , metabolic syndrome , statistic , obesity , cardiology , risk factor , psychology , psychiatry , mathematics , statistics , psychotherapist
Objective. To find the association between cognitive function and cardiovascular risk factors and to develop statistic model. Results. Our study demonstrated that cognitive dysfunction is more profound in middle-aged patients with metabolic syndrome (MS) compared to the individuals with single risk factors without MS. Multiple regression analysis defined glucose (β = 0,0114) and systolic blood pressure (SBP) (β = -0,212) to be factors related with MMSE-test results. When glucose level was excluded from the model, the following factors were shown to be significant: SBP (β = -0,202), age (β = -0,093), operative memory (β = -0,169), total cholesterol level (β = -0,065), therapy by calcium antagonist (β = 0,082), obesity (β = 0,06), R = 92 %.