Open AccessLevels of nitric oxide metabolites in patients with asthma and concomitant hypertension
Author(s) -
А. Г. Козырев,
А Ю Гичкин,
А. А. Жлоба
Publication year - 2010
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 5
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2010-16-3-266-269
Subject(s) - concomitant , asthma , medicine , nitric oxide , exacerbation , asthma exacerbations , cardiology
Objective. To investigate plasma levels of nitrates/nitrites (NO2+NO3) and S-nitrosothiols in asthmatic patients, including patients with concomitant arterial hypertension. Methods. The data were obtained by Greiss method before and after treatment of asthma exacerbation in asthmatic patients and healthy subjects. Results. This study has shown that evaluation of NO2+NO3 and S-nitrosothiols should consider asthma severity and the presence of concomitant arterial hypertension. The level of NO metabolites was higher in mild asthma and in patients with concomitant hypertension of grade 1.