Open AccessMineralocorticoid excess and left ventricular hypertrophy
Author(s) -
А. В. Барсуков,
З. В. Багаева,
Д. В. Кадин,
В. Л. Баранов,
С Б Шустов
Publication year - 2008
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 5
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2008-14-3-211-218
Subject(s) - ventricle , primary aldosteronism , medicine , left ventricular hypertrophy , mineralocorticoid , cardiology , aldosterone , muscle hypertrophy , diastole , mineralocorticoid receptor , concentric hypertrophy , diastolic function , endocrinology , blood pressure
Primary aldosteronism is one of the most prevalent reasons of secondary hypertension. Mineralocorticoid excess is on independent powerful pathogenic factor of left ventricular hypertrophy and its diastolic dysfunction. The degree of participation of aldosterone precursors in left ventricular remodeling is unknown. Two case reports concerning the peculiarities of different mineralocorticoid influence on left ventricle structure and function are described in the paper.