Open AccessCorrection of endothelial function in hypertension associated with tyberculosis by fixed combination of perindopril and indopamide
Author(s) -
N. Yu. Klimenko,
N. V. Drobotya,
A. A. Kastanyan,
В. В. Калтыкова,
E. Sh. Guseynova
Publication year - 2007
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 5
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2007-13-4-256-261
Subject(s) - perindopril , indapamide , medicine , blood pressure , cardiology , endothelial dysfunction , vasodilation , endothelium
A study of daily blood pressure (BP) dynamics, functional endothelial condition at hypertensive patients in combination with tuberculosis of various localization and estimation of an opportunity of correction of the revealed disturbances during 12-week therapy by the fixed combination of perindopril and indapamide - noliprel-forte (Servier, France) were performed. During research more expressed endothelial dysfunction at hypertensive patients, proceeding on a background of tubercular process in comparison with patients with isolated arterial hypertension was revealed. Therapy by noliprel-forte provided the reliable 24-hour control of BP level, which was accompanied by endothelial function normalization that was shown by improvement of a endothelium-dependent vasodilatation and decrease of a von Willebrand factor level. .