Open AccessComparison of efficacy of fixed combinations of verapamil SR+ trandolapril and captopril + HCTZ in high risk hypertensive patients
Author(s) -
С. В. Недогода,
Tawfik Chalabi,
В. В. Цома,
U. A. Brel
Publication year - 2007
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 5
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2007-13-2-141-144
Subject(s) - trandolapril , hydrochlorothiazide , blood pressure , captopril , medicine , verapamil , tolerability , cardiology , left ventricular hypertrophy , benazepril , urology , ace inhibitor , angiotensin converting enzyme , calcium , adverse effect
The blinded randomized study the clinical effecacy and tolerability during 6 month therapy with one of two fixed combinations Tarka (verapamil SR+trandolapril) and Capozide (captopril+HCTZ) were compared patients (20 patients at every group) with arterial hypertension who did not achiev target blood pressure on monotherapy. Tarka was more effective decreased of left ventricular hypertrophy and improved vascular elasticity. Tarka also had better T/P coefficient. Tarka improved glucose level, Capozide worsen potassium levels.