
Acetazolamide in the treatment of sleep apnea m adults and childi en
Author(s) -
Ольга Владимировна Быкова,
Л. М. Кузенкова,
О. И. Маслова,
А. Н. Бойко
Publication year - 2006
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 5
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2006-12-4-365-368
Subject(s) - acetazolamide , medicine , pediatrics , apnea , central sleep apnea , sleep apnea , obstructive sleep apnea , anesthesia , disease , population , polysomnography , environmental health
Obstructive sleep apnea syndrome (OSA) is life-threatening condition in adults and children. Prevalence of OSA in adult and pediatric population is not well-established as not all patients have clear clinical picture. In Britain prevalence of OSA syndrome is comparable to asthma disease. Acetazolamide can cause metabolic acidosis, which can stimulate pulmonary ventilation and proposed to be effective in treatment of sleep breathing disturbances. Acetazolamide is widely used to therapeutic treatment of central OSA in adults and children. In adults administration of this drug can have problems of tolerance if administrated chronically. Alternatively, in children, OSA is usually transitory condition is early childhood what allow to treat it with acetazolamide effectively.