Open AccessSympathetic nervous system and serum leptin level in obese patients with and without obstructive sleep apnea
Author(s) -
Н. Э. Звартау,
Yurii Sviryaev,
O. P. Rotari,
I. Emelyanov,
N. K. Merculova,
A. Ο. Conrady,
А. Л. Калинкин
Publication year - 2006
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 5
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2006-12-3-256-261
Subject(s) - obstructive sleep apnea , medicine , leptin , sympathetic nervous system , hypercapnia , obesity , hypoxia (environmental) , sympathetic activity , sleep apnea , endocrinology , apnea , blood pressure , autonomic nervous system , sleep (system call) , respiratory system , heart rate , chemistry , organic chemistry , oxygen , computer science , operating system
The aim of the present study was to investigate sympathetic nervous system activity and serum leptin level in obese patients with and without obstructive sleep apnea (OSA). We examined 75 OSA patients and 40 age, weight, BMI and blood pressure levels matched obese patients without OSA. As a result, patients with OSA had higher sympathetic activity associated not only with repetitive episodes of hypoxia/hypercapnia during sleep, but also with more marked central obesity and higher serum leptin level.