Open AccessClinical Efficacy of foxed low-dose perindopril-indapamide combination in the elderly
Author(s) -
А. И. Кирсанов,
И. А. Горбачева,
Л. А. Шестакова
Publication year - 2006
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 5
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2006-12-3-244-247
Subject(s) - perindopril , indapamide , metoprolol , medicine , blood pressure , fixed dose combination , heart rate , pharmacology , cardiology
The study addresses antihypertensive effects of fixed low-dose perindopril-indapamide combination therapy in the elderly hypertensive patients. Combinations with metoprolol were also studied. Is was shown that antihypertensive effect can be observed ay second week of treatment and is dose-dependent. Besides, additional administration of metoprolol 50 mg per day was not associated with further blood pressure decrease but resulted in significant heart rate reduction.