Open AccessInfluence of therapy of metoprolol on some indices of central nervous system, diastolic function of myocardium and exercise training test in patient with stable angina pectoris II-III and arterial hypertension I-II
Author(s) -
Е. В. Пармон,
Э. Р. Бернгардт,
Т. В. Трешкур,
М. А. Овечкина,
Е. В. Шляхто
Publication year - 2006
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 5
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2006-12-2-165-172
Subject(s) - medicine , metoprolol , cardiology , ventricle , angina , blood pressure , treadmill , diastole , myocardial infarction
The article reveals the results of original study about effects of therapy of metoprolol (“Metocard”, Polfarma) in 32 patients with stable angina pectoris II-III and arterial hypertension I-II. Average maximal effective and well-tolerated dose of Metocard was 93,0±5,62 mg per day. The 24-hour monitoring of blood pressure and ECG, as well as treadmill test, biochemical analyses, Echo-CG, MMPI, and the Midlsec tests were performed before and six weeks after the treatment onset. It’s effective antiischemic, hypotensive and antiarrhythmic actions were revealed. Metocard demonstrated positive influence on cognitive functions and psychoemotional status of patients; there were no any negative influences on lipid metabolism and diastolic function of left ventricle.