Open AccessAssociation of betaxolol therapy with the clinical and functional parameters in patients with essential hypertension
Author(s) -
А. В. Шабалин,
Ye. N. Gulyaeva,
А. С. Криковцов
Publication year - 2005
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 5
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2005-11-4-261-264
Subject(s) - betaxolol , medicine , blood pressure , cardiology , rhythm , quality of life (healthcare) , autonomic nervous system , anesthesia , heart rate , surgery , intraocular pressure , timolol , nursing
The association of clinical and functional parameters was studied in patients with mild and moderate arterial hypertension (All) during therapy with betaxolol (Lokren), Twenty six patients (19 males and 7 females) aged 28 to 56 (mean 40.5 ± 1.4) years who had grade 1-2 AH were examined. The patients received monotherapy with betaxolol in a single dose of 10 mg/day. 24-hour ECG and blood pressure monitoring, stress-echocardiography during the arithmetic test estimating cognitive functions and life quality by the SP-36 scale were performed at the baseline and following 8 weeks of therapy. It has been found that betaxolol (Lokren) used In a single dose of 10 mg/day for 8 weeks has a high antihypertensive efficacy, stabilizes the autonomic balance of cardiac rhythm regulation, by simultaneously showing antiarrhythmic properties, reduces the degree of stress responsiveness, and enhances the inhibition of the central nervous system, by ultimately improving the quality of life in the patients.