Open AccessEffect of insulin on the functional status of the pituitary-gonadal system In males with arterial hypertension
Author(s) -
Н. Иванов,
Наталья Владимировна Ворохобина,
С. К. Чурина
Publication year - 2004
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 5
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2004-10-1-46-48
Subject(s) - medicine , endocrinology , hormone , testosterone (patch) , insulin , gonadal hormones , biology , castration
The study was undertaken to examine the metabolism and blood levels of major adrenal and gonadal androgens and the relationship between the levels of insulin and major steroid hormones in males with untreated arterial hypertension (AH). A hundred and twenty-five patients with AH and 15 healthy males matched by age who made up a control group. The males with AH had low levels of free testosterone, dihydroepiandrosterone sulfate and high concentrations of insulin as compared with the control group. The values of gonadotropic hormones, estradiol and cortisol did not differ in the comparable groups. There was a negative correlation between the levels of free testosterone, dihydroepiandrosterone sulfate, and insulin in patients with AH.