Open AccessMagnesium homeostasis in patients with arterial hypertension and coronary heart disease: potentialities of correction with magnesium preparations
Author(s) -
О. И. Левина,
В. Л. Макаров,
С. К. Чурина
Publication year - 2004
Publication title -
arterialʹnaâ gipertenziâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.126
H-Index - 5
eISSN - 2411-8524
pISSN - 1607-419X
DOI - 10.18705/1607-419x-2004-10-1-25-28
Subject(s) - magnesium , blood pressure , homeostasis , medicine , angina , cardiology , endocrinology , excretion , coronary heart disease , chemistry , myocardial infarction , organic chemistry
Twenty-one patients with coronary heart disease, functional classes I-II angina pectoris concurrent with moderate arterial hypertension were examined. Magnesium preparations were studied for their effect on blood pressure values, ECG parameters, and exercise tolerance during a bicycle ergometric test, as well as serum lipid profile and some membranous ion-transporting systems in the red blood cells. Exogenous magnesium was not found to have any effect on blood pressure. The administration of magnesium preparations promotes a decrease in urinary excretion of magnesium and an increase in its intracellular concentration, positively affects its homeostasis and the metabolism of other elements related to the development of vascular abnormalities.