Association of nineteen polymorphisms from seven DNA repair genes and the risk for bladder cancer in Gansu province of China | Zendy

Gongjian Zhu | Zendy; Haixiang Su | Zendy; Lingeng Lu | Zendy; Hongyun Guo | Zendy; Zhaohui Chen | Zendy; Zhen Sun | Zendy; Ruixia Song | Zendy; Xiaomin Wang | Zendy; Haining Li | Zendy; Zhiping Wang | Zendy

Open Access

Association of nineteen polymorphisms from seven DNA repair genes and the risk for bladder cancer in Gansu province of China

Author(s) -

Gongjian Zhu,

Haixiang Su,

Lingeng Lu,

Hongyun Guo,

Zhaohui Chen,

Zhen Sun,

Ruixia Song,

Xiaomin Wang,

Haining Li,

Zhiping Wang

Publication year - 2016

Publication title -

oncotarget

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.373

H-Index - 127

ISSN - 1949-2553

DOI - 10.18632/oncotarget.9146

Subject(s) - medicine , bladder cancer , oncology , single nucleotide polymorphism , mutyh , cancer , traditional medicine , genotype , genetics , dna repair , biology , gene , dna glycosylase

Balance of DNA damage and proper repair plays an important role in progression of bladder cancer. Here we aimed to assess the associations of nineteen polymorphisms from seven DNA repair-associated genes (PRAP1, OGG1, APEX1, MUTYH, XRCC1, XRCC2 and XRCC3) with bladder cancer and their interactions in the disease in a Han Chinese population.

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