Open AccessAssociation of nineteen polymorphisms from seven DNA repair genes and the risk for bladder cancer in Gansu province of China
Author(s) -
Guanbao Zhu,
Hongling Su,
Lingeng Lu,
Hongyun Guo,
Zhaohui Chen,
Zhen Sun,
Ruixia Song,
Xiaomin Wang,
Haining Li,
Zhiping Wang
Publication year - 2016
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.9146
Subject(s) - medicine , bladder cancer , oncology , single nucleotide polymorphism , mutyh , cancer , traditional medicine , genotype , genetics , dna repair , biology , gene , dna glycosylase
Balance of DNA damage and proper repair plays an important role in progression of bladder cancer. Here we aimed to assess the associations of nineteen polymorphisms from seven DNA repair-associated genes (PRAP1, OGG1, APEX1, MUTYH, XRCC1, XRCC2 and XRCC3) with bladder cancer and their interactions in the disease in a Han Chinese population.