Open AccessHigh expression of C-C chemokine receptor 2 associates with poor overall survival in gastric cancer patients after surgical resection
Author(s) -
Ruochen Li,
Heng Zhang,
Hao Líu,
Chao Lin,
Yifan Cao,
Weijuan Zhang,
Zhongliang Shen,
Jiejie Xu
Publication year - 2016
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.8069
Subject(s) - ccr2 , medicine , cancer , chemokine receptor , stage (stratigraphy) , oncology , immunohistochemistry , proportional hazards model , chemokine , cancer research , receptor , biology , paleontology
Being a critical chemokine receptor in chemoattracting myeloid cells into tumor tissues, C-C chemokine receptor 2 (CCR2) has been detected in many malignant tumors. This study aims to evaluate the prognostic value of CCR2 expression in patients with gastric cancer after surgery.