Oncogene and therapeutic target analyses in atypical fibroxanthomas and pleomorphic dermal sarcomas | Zendy

Doris Helbig | Zendy; Michaela A. Ihle | Zendy; Katharina Pütz | Zendy; Iliana TantchevaPoór | Zendy; Cornelia Mauch | Zendy; Reinhard Büttner | Zendy; Alexander Quaas | Zendy

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Oncogene and therapeutic target analyses in atypical fibroxanthomas and pleomorphic dermal sarcomas

Author(s) -

Doris Helbig,

Michaela A. Ihle,

Katharina Pütz,

Iliana TantchevaPoór,

Cornelia Mauch,

Reinhard Büttner,

Alexander Quaas

Publication year - 2016

Publication title -

oncotarget

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.373

H-Index - 127

ISSN - 1949-2553

DOI - 10.18632/oncotarget.7845

Subject(s) - hras , cdkn2a , cancer research , atypical fibroxanthoma , carcinogenesis , immunohistochemistry , oncogene , neuroblastoma ras viral oncogene homolog , pathology , biology , amplicon , kras , mutation , cancer , medicine , gene , cell cycle , genetics , polymerase chain reaction

Until now, almost nothing is known about the tumorigenesis of atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS). Our hypothesis is that AFX is the non-infiltrating precursor lesion of PDS.

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