Open AccessSerum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease
Author(s) -
Satish Kumar Ramraj,
Sheeja Aravindan,
Dinesh Babu Somasundaram,
Terence S. Herman,
Mohan Natarajan,
Natarajan Aravindan
Publication year - 2016
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.7615
Subject(s) - microrna , neuroblastoma , biomarker , tumor progression , medicine , gene silencing , oncology , disease , cancer research , metastasis , cancer , bioinformatics , biology , genetics , gene , cell culture
Circulating miRNAs have momentous clinical relevance as prognostic biomarkers and in the progression of solid tumors. Recognizing novel candidates of neuroblastoma-specific circulating miRNAs would allow us to identify potential prognostic biomarkers that could predict the switch from favorable to high-risk metastatic neuroblastoma (HR-NB).