Open AccessIntrapleural targeted therapies (anti-VEGF and anti-EGFR) in the model of malignant pleural effusion
Author(s) -
Milena Marques Pagliarelli Acencio,
Juliana Puka,
Vanessa Alvarenga,
Vanessa Martins,
Mariana Carvalho,
Evaldo Marchi,
Vera Luíza Capelozzi,
Lisete R. Teixeira
Publication year - 2017
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.21362
Subject(s) - kras , medicine , malignant pleural effusion , cancer research , egfr inhibitors , pleural effusion , epidermal growth factor receptor , vascular endothelial growth factor , pathology , cancer , colorectal cancer , vegf receptors
Malignant pleural effusion has few options of treatment and drugs administrated by different routes can lead to a less permissive microenvironment for the development of malignant pleural disease.