Open AccessAssociation between SNPs in microRNA machinery genes and gastric cancer susceptibility, invasion, and metastasis in Chinese Han population
Author(s) -
Xingbo Song,
Huiyu Zhong,
Qian Wu,
Minjin Wang,
Juan Zhou,
Yi Zhou,
Xiaojun Lu,
Binwu Ying
Publication year - 2017
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.21199
Subject(s) - single nucleotide polymorphism , microrna , gene , cancer , genetics , biology , metastasis , genotype , medicine , snp , chinese population , han chinese , oncology , cancer research
The present study investigates the influence of genetic variants in miRNA machinery genes ( DROSHA, DICER, AGO1 , and GEMIN4 ) on gastric cancer in Chinese Han population, further revealing the genetic mechanisms of gastric cancer occurrence and development.