Open AccessAlpha lipoic acid attenuates radiation-induced oral mucositis in rats
Author(s) -
Jin Hyun Kim,
Myeong Hee Jung,
Jin Pyeong Kim,
Hyun-Jung Kim,
Jung Hwa Jung,
Jong Ryeal Hahm,
Ki Mun Kang,
Bae Kwon Jeong,
Seung Hoon Woo
Publication year - 2017
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.20286
Subject(s) - mucositis , medicine , radiation therapy , gastroenterology
Radiotherapy is currently one of the main treatment modalities for head and neck cancer; however, it also results in severe toxicity to the normal tissue, to the detriment of patients. This study aimed to investigate whether alpha lipoic acid (ALA) could protect against radiation-induced oral mucositis in a rat model.