Open AccessmRNA expression profiles obtained from microdissected pancreatic cancer cells can predict patient survival
Author(s) -
Ana-Bárbara García-García,
M. Carmen Gómez-Mateo,
Rebeca Hilario,
Pilar Rentero-Garrido,
Álvaro MartínezDoménech,
Verónica González-Albert,
Andrés Cervantes,
Pablo Marín-Garcia,
Felipe Javier Chaves,
Antonio FerrándezIzquierdo,
Luís Sabater
Publication year - 2017
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.20076
Subject(s) - valencia , medicine , garcia , humanities , biology , art , ecology
Pancreatic ductal adenocarcinoma (PDAC) is one of the most devastating malignancies in developed countries because of its very poor prognosis and high mortality rates. By the time PDAC is usually diagnosed only 20-25% of patients are candidates for surgery, and the rate of survival for this cancer is low even when a patient with PDAC does undergo surgery. Lymph node invasion is an extremely bad prognosis factor for this disease.