Open AccessPrognostic significance of GSTP1 in patients with triple negative breast cancer
Author(s) -
Guanglei Chen,
Hao Zhang,
Lisha Sun,
Yanlin Jiang,
Zhen Xu,
Huizi Gu,
Hong Xu,
Jie Yang,
Yining Wang,
Ting Xu,
Yingchao Zhang,
Caigang Liu
Publication year - 2017
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.19824
Subject(s) - gstp1 , medicine , breast cancer , oncology , china , cancer , zhàng , triple negative breast cancer , genotype , biology , gene , biochemistry , political science , law
Previous studies showed that glutathione S-transferase Pi 1 (GSTP1) is a critical metabolic driver that is heightened specifically in triple negative breast cancer (TNBC) and drives breast cancer pathogenicity. This study focuses on investigating the relationship between the expression of the GSTP1 protein and TNBC metastasis and prognosis in China.