Low-dose photon irradiation induces invasiveness through the SDF-1α/CXCR4 pathway in malignant mesothelioma cells | Zendy

Yoshikane Yamauchi | Zendy; Seyer Safi | Zendy; Lena Orschiedt | Zendy; Adriane Gardyan | Zendy; Stephan Brons | Zendy; Juliane Rieber | Zendy; Nils H. Nicolay | Zendy; Peter E. Huber | Zendy; Martin E. Eichhorn | Zendy; Hendrik Dienemann | Zendy; Felix J.F. Herth | Zendy; KlausJosef Weber | Zendy; Jürgen Debus | Zendy; Hans Hoffmann | Zendy; Stefan Rieken | Zendy

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Low-dose photon irradiation induces invasiveness through the SDF-1α/CXCR4 pathway in malignant mesothelioma cells

Author(s) -

Yoshikane Yamauchi,

Seyer Safi,

Lena Orschiedt,

Adriane Gardyan,

Stephan Brons,

Juliane Rieber,

Nils H. Nicolay,

Peter E. Huber,

Martin E. Eichhorn,

Hendrik Dienemann,

Felix J.F. Herth,

KlausJosef Weber,

Jürgen Debus,

Hans Hoffmann,

Stefan Rieken

Publication year - 2017

Publication title -

oncotarget

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.373

H-Index - 127

ISSN - 1949-2553

DOI - 10.18632/oncotarget.19134

Subject(s) - mesothelioma , cancer research , medicine , cxcr4 , irradiation , pathology , receptor , physics , chemokine , nuclear physics

Low-dose photon irradiation has repeatedly been suspected to increase a risk of promoting local recurrence of disease or even systemic dissemination. The purpose of this study was to investigate the motility of malignant pleural mesothelioma (MPM) cell lines after low-doses of photon irradiation and to elucidate the mechanism of the detected phenotype.

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