High expression of FUT3 is linked to poor prognosis in clear cell renal cell carcinoma | Zendy

Li Meng | Zendy; Le Xu | Zendy; Yuanfeng Yang | Zendy; Lin Zhou | Zendy; Yuan Chang | Zendy; Tianming Shi | Zendy; Cheng Tan | Zendy; Huimin An | Zendy; Yu Zhu | Zendy; Jiejie Xu | Zendy

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High expression of FUT3 is linked to poor prognosis in clear cell renal cell carcinoma

Author(s) -

Li Meng,

Le Xu,

Yuanfeng Yang,

Lin Zhou,

Yuan Chang,

Tianming Shi,

Cheng Tan,

Huimin An,

Yu Zhu,

Jiejie Xu

Publication year - 2017

Publication title -

oncotarget

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.373

H-Index - 127

ISSN - 1949-2553

DOI - 10.18632/oncotarget.17717

Subject(s) - fucosyltransferase , medicine , clear cell renal cell carcinoma , nomogram , renal cell carcinoma , oncology , fucosylation , lymphovascular invasion , cancer research , cancer , biology , microbiology and biotechnology , gene , metastasis , biochemistry , glycoprotein , glycan

Some of the fucosylation catalyzed by fucosyltransferase-III mediates the epithelial-mesenchymal transition and enhances tumor cell-macrophage signaling, which promotes malignant transforming and immune evasion. The aim of the study was to investigate the association between the expression of fucosyltransferase-III and clinical outcomes of patients with clear-cell renal cell carcinoma after surgery.

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