Open AccessPrognosis of surgery combined with different adjuvant therapies in esophageal cancer treatment: a network meta-analysis
Author(s) -
Shenglei Li,
Hongtao Liu,
Changying Diao,
Xiaohui Wang,
Ming Gao,
Zong-Ming Li,
Lijie Song,
Xiaoning Gao,
Jing Han,
Feng Wang,
Wencai Li,
Xinwei Han
Publication year - 2017
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.16193
Subject(s) - medicine , esophageal cancer , meta analysis , chemoradiotherapy , radiation therapy , oncology , cancer , general surgery
This network meta-analysis was conducted to assess whether the efficacy of surgery with adjuvant therapies, including radiotherapy (RT+S), chemotherapy (CT+S), and chemoradiotherapy (CRT+S) have better performance in esophageal cancer treatment and management. PubMed and EMBASE were used to search for relevant trials. Both conventional pair-wise and network meta-analyses were carried out. The surface under the cumulative ranking curve (SUCRA) was used to rank interventions based on the efficacy of the treatment method. As for 3-year overall survival (OS), CRT+S showed the highest efficacy (CRT+S vs.