The gamma-glutamyl transpeptidase to platelet ratio for non-invasive assessment of liver fibrosis in patients with chronic hepatitis B and non-alcoholic fatty liver disease | Zendy

Qiang Li | Zendy; Chuan Lu | Zendy; Weixia Li | Zendy; Yuxian Huang | Zendy; Liang Chen | Zendy

Open Access

The gamma-glutamyl transpeptidase to platelet ratio for non-invasive assessment of liver fibrosis in patients with chronic hepatitis B and non-alcoholic fatty liver disease

Author(s) -

Qiang Li,

Chuan Lu,

Weixia Li,

Yuxian Huang,

Liang Chen

Publication year - 2017

Publication title -

oncotarget

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.373

H-Index - 127

ISSN - 1949-2553

DOI - 10.18632/oncotarget.16162

Subject(s) - medicine , gastroenterology , cirrhosis , fibrosis , receiver operating characteristic , aspartate transaminase , fatty liver , steatohepatitis , disease , alkaline phosphatase , biochemistry , chemistry , enzyme

The gamma-glutamyl transpeptidase-to-platelet ratio (GPR) is a novel serum model, which was reported more accurate than aspartate transaminase-to-platelet ratio index (APRI) and fibrosis index based on four factors (FIB-4) for diagnosing significant fibrosis and cirrhosis in HBV mono-infection in West Africa. We aimed to evaluate the diagnostic performance of GPR for liver fibrosis in patients with chronic hepatitis B (CHB) and non-alcoholic fatty liver disease (NAFLD).

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