Open AccessAre neurological complications of monoclonal gammopathy of undetermined significance underestimated?
Author(s) -
Normann Steiner,
Angelika Schwärzler,
Georg Göbel,
Wolfgang N. Löscher,
Julia Wanschitz,
Eberhard Gunsilius
Publication year - 2016
Publication title -
oncotarget
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.373
H-Index - 127
ISSN - 1949-2553
DOI - 10.18632/oncotarget.13861
Subject(s) - monoclonal gammopathy of undetermined significance , medicine , monoclonal gammopathy , pathology , monoclonal , immunology , monoclonal antibody , antibody
Monoclonal gammopathy of undetermined significance (MGUS) is a premalignancy preceding multiple myeloma (MM) or related disorders. Neurological symptoms caused by the monoclonal immunoglobulins or free light-chains are often associated with a high morbidity. We analyzed the prevalence of neuropathy, clinical features and the long-term outcome in 223 patients (pts.) with MGUS.