Open AccessSubclinical atherosclerosis and immune activation in young HIV-infected patients with telomere shortening
Author(s) -
María José Alcaraz,
Antonia Alcaráz,
Raúl TeruelMontoya,
José A. Campillo,
Alejandro de la Torre,
Ángeles Muñoz,
Cristina Tomás,
Gabriel Puche,
Carlos Báguena,
Alfredo Cano,
Alfredo Minguela,
Enrique Bernal
Publication year - 2021
Publication title -
aging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.203350
Subject(s) - cd38 , cd8 , immune system , medicine , premature aging , subclinical infection , immunology , lymphocyte , senescence , telomere , young adult , inflammation , biology , physiology , cd34 , stem cell , dna , genetics
To date, available data on premature aging in young HIV-infected adults are scarce and no reports offer comprehensive assessment of telomere shortening (TS) in relation to subclinical atherosclerosis (SCA). In this study, we investigate if telomere shortening and immune activation markers are associated with SCA, which is one of the main degenerative diseases in young HIV-infected adults.