Mendelian randomization as an approach to assess causal effects of inflammatory bowel disease on atrial fibrillation | Zendy

Laite Chen | Zendy; Xia Sheng | Zendy; Chenyang Jiang | Zendy

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Mendelian randomization as an approach to assess causal effects of inflammatory bowel disease on atrial fibrillation

Author(s) -

Laite Chen,

Xia Sheng,

Chenyang Jiang

Publication year - 2021

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.202906

Subject(s) - mendelian randomization , genome wide association study , medicine , odds ratio , confounding , single nucleotide polymorphism , genetic association , inflammatory bowel disease , disease , genetics , biology , genetic variants , genotype , gene

Despite growing evidence indicating that patients with inflammatory bowel disease (IBD) have an increased risk of atrial fibrillation (AF), owing to the potential biases of confounding effects and reverse causation, the specific relationship between IBD and AF remains controversial. The aim of this study is to determine whether there is a causal effect of IBD on AF.

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