β cell aging and age-related diabetes | Zendy

Min Zhu | Zendy; Xiaohong Liu | Zendy; Wen Liu | Zendy; Yanrong Lu | Zendy; Jingqiu Cheng | Zendy; Younan Chen | Zendy

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β cell aging and age-related diabetes

Author(s) -

Min Zhu,

Xiaohong Liu,

Wen Liu,

Yanrong Lu,

Jingqiu Cheng,

Younan Chen

Publication year - 2021

Publication title -

aging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.473

H-Index - 90

ISSN - 1945-4589

DOI - 10.18632/aging.202593

Subject(s) - type 2 diabetes , diabetes mellitus , insulin resistance , senescence , pathogenesis , medicine , viewpoints , bioinformatics , gerontology , biology , endocrinology , art , visual arts

Type 2 diabetes is characterized by insulin resistance and loss of β cell mass and function. Aging is considered as a major risk factor for development of type 2 diabetes. However, the roles of pancreatic β cell senescence and systemic aging in the pathogenesis of type 2 diabetes in elderly people remain poorly understood. In this review, we aimed to discuss the current findings and viewpoints focusing on β cell aging and the development of type 2 diabetes.

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