Open AccessPre-incubation with human umbilical cord derived mesenchymal stem cells-exosomes prevents cisplatin-induced renal tubular epithelial cell injury
Author(s) -
Zongying Li,
Shuyi Cao
Publication year - 2020
Publication title -
aging (albany, n.y. online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.473
H-Index - 90
ISSN - 1945-4589
DOI - 10.18632/aging.103545
Subject(s) - microvesicles , mesenchymal stem cell , viability assay , apoptosis , chemistry , mtt assay , microbiology and biotechnology , flow cytometry , cisplatin , stem cell , cell , biology , cancer research , microrna , biochemistry , genetics , chemotherapy , gene
The administration of cisplatin is limited due to its nephrotoxicity, and prevention of this nephrotoxicity of cisplatin is difficult. Mesenchymal stem cell (MSC)-derived exosomes have been implicated as a novel therapeutic approach for tissue injury.