MMP-9 Level Comparation between Spontaneous Abortion and Normal Pregnancy | Zendy

Aloysius Suryawan | Zendy; Johanes C. Mose | Zendy; Budi Handono | Zendy

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MMP-9 Level Comparation between Spontaneous Abortion and Normal Pregnancy

Author(s) -

Aloysius Suryawan,

Johanes C. Mose,

Budi Handono

Publication year - 2012

Publication title -

the indonesian biomedical journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.16

H-Index - 4

eISSN - 2355-9179

pISSN - 2085-3297

DOI - 10.18585/inabj.v4i3.178

Subject(s) - abortion , medicine , obstetrics , miscarriage , pregnancy , gynecology , obstetrics and gynaecology , medical abortion , products of conception , gestational age , misoprostol , genetics , biology

BACKGROUND: Abortion remains a problem in the obstetric care as it is one of the causes of maternal and fetal death. Bleeding or miscarriage threat in the first trimester comprises 20% to 25% of all pregnant women, and 50% of them will end as spontaneous abortion. The major cause of maternal death in abortion is hemorrhage. Some recent studies have indicated that MMP-9 is important in the process of embryo implantation into the endometrium and spontaneous abortion occurs when there is an overwhelming increase of MMP-9. This data indicate the importance of a further research to elucidate the role of MMP-9 in spontaneous abortion.METHODS: This was a cross sectional study, included 70 pregnant women with gestational age 1221.7 with the sensitivity of 48.6% specificity of 80%, and accuracy of 60.9%.SUMMARY: The MMP-9 level in spontaneous abortion was higher than in normal pregnancy.KEYWORDS: MMP-9, spontaneous abortion, normal pregnancy

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